OYE Therapeutics

Invest in OYE - invest in the future 

OYE anticipates completing a near term clinical development and regulatory milestone upon receipt of the full readout of our Phase II human clinical study Q3/2022. 

Value Proposition

​"Open Your Eyes" is traditionally the first instruction you hear upon waking from general anesthesia following a medical procedure. OYE is making that safer for the patient and the medical professional. It's also our internal mandate to improve the patient experience through observation of the clinical process. Our mission is to save lives by filling gaps in care that have been overlooked.

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ABL, Adaptive Business Leaders, Bay Area have named O.Y.E. Therapeutics as one of its “Innovators in Healthcare” for 2021 

Brett Dines, O.Y.E.’s CEO, was one of three presenters/awardees who spoke at ABL’s 24th Innovations in Healthcare ~ Bay Area Edition on December 8, 2021. According to ABL’s announcement regarding the event, “This year’s “Innovators in Healthcare” saw opportunities where others saw only the problems.” As for O.Y.E., “Brett Dines, CEO of OYE Therapeutics, knew the stats: “delayed emergence” from the coma-like state created by anesthesia contributes to over 32,000 deaths, 2.4 million extra days of post-surgical hospitalization, and $9.3 billion in added OR expenses each year. The good news is that Brett’s team is working on the solution.” Brett’s presentation focused not only on delayed emergence, but also the other clinical programs currently being researched at the pharmaceutical development company. In keeping with the times, Brett’s presentation was virtual, as was the entire conference. Other “attendees” included Robert Funari, Chairperson of O.Y.E.’s Board, who was invited to introduce Mr. Dines. Mr. Funari concurred with ABL as to the innovation he witnessed from his current position at OYE as well as from his long-standing professional association with the CEO. 


O.Y.E. is located at the Purdue Research Park of Northwest Indiana. They focus on identifying “gaps in medical care” and filling those gaps through innovative therapeutic solutions. Their goals are to directly save lives while improving the quality of care for all patients. Michael Hicks, COO, said, “O.Y.E. is built on Brett Dine’s vision. A unique opportunity presented itself and Brett recognized the ability to make a difference in healthcare. That one decision - to move forward because it would help - spawned the philosophy that drives all of O.Y.E.’s goals, both operational and aspirational.”
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O.Y.E. Therapeutics announces successful pre-IND meeting with FDA

O.Y.E. Therapeutics, a clinical-stage pharmaceutical development company with a drug targeted at expediting emergence from anesthesia, has announced a successful pre-IND (Investigational New Drug) meeting with the U.S. Food and Drug Administration.

A pre-IND meeting provides an opportunity for a drug development company and the FDA to discuss the drug's development plan and to obtain the agency's guidance for clinical studies of the company's new drug candidate.

"We are grateful for the guidance from the FDA as we move into our next phase of research," said Brett Dines, O.Y.E. CEO. "They were helpful as to what they wished to see regarding the safety profile of our product. They also offered feedback that our trial design would be effective at demonstrating efficacy in their eyes.

Read more at Purdue.edu
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Research agreement focuses
on battlefield injuries

OYE Therapeutics Inc., a Purdue University-affiliated company, is working to reduce the mortality and morbidity resulting from injuries on the battlefield through the development of new life-saving strategies.

OYE is located in the Purdue Technology Center in the Purdue Research Park of Northwest Indiana.

The company has entered into a Cooperative Research and Development Agreement (CRADA) with the Uniformed Services University of the Health Sciences (USU), an institution of higher learning within the U.S. Department of Defense and The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc. (HJF).

The partnership includes researching the effectiveness of OYE-002 to enhance acute pain control at the point-of-injury, cognitive processing, psychomotor resilience and mission capabilities.

Read more at Purdue.edu